Check out the full article in Frontiers in Neurology:

Article/Study Title

“Imaging the Visual Network in the Migraine Spectrum”


Francesca Puledda, Dominic Ffytche, Owen O’Daly, and Peter J. Goadsby


“Modern neuroimaging has allowed to detect several functional, structural and metabolic changes affecting multiple elements of the visual network in migraineurs, both with and without aura. These abnormalities help explain some of the key features of the condition, such as abnormal sensory processing, photophobia and the aura phenomenon, and further link it to the growingly recognized neurological syndrome of visual snow. In this condition, which is likely on a similar pathophysiological spectrum as migraine, multiple elements (i.e., cortical hypermetabolism, thalamo-cortical dysrhythmia, brain network dysfunctions) could be at play in the generation of a persistent visual illusion.”

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“Ten years ago, in 2012, we presented work at a neurology meeting systematically describing why Visual Snow was not simply migraine aura and was a distinct disease entity. This was not received with universal acclaim, to say the least. In the intervening period, visual snow has come in from the medical ‘cold’ and is being studied actively by a number of groups on three continents. The recognition of the condition, broadening education, and funding research would not have happened were it not for the Visual Snow Initiative. I realize to the many with this often very disabling condition that it seems nothing has or is being done. Progress to treatment is never fast enough nor advances to recognition and understanding. With that said, visual snow research would be idling in a backwater where it not the Initiative. Going forward, we need to double, re-double, and re-double again our efforts for the search for effective treatments and, one day, a cure. Thank you for the Visual Snow Initiative for all you have done and continue to do.”

— Peter Goadsby, MD, PhD, DSc, Professor of Neurology, UCLA, Awarded 2021 Brain Prize

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