Active VSI-Funded Visual Snow Syndrome Studies

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All donations to the Visual Snow Initiative (VSI) go directly to Visual Snow Syndrome research. Details regarding the Visual Snow Syndrome (VSS) research being funded by the VSI can be found below.

Thank you so much to all of our supporters and global VSS researchers for your diligence and passion towards helping us find solutions for VSS!


Current areas of study for VSI-funded research include:

• Identifying biomarkers and further understanding those which have recently been identified (i.e. abnormalities in serotoninergic and glutamatergic neurotransmission)

 Understanding the pathophysiology and underlying mechanisms of VSS as a network disorder

Using this data to identify potential safe, targeted, and effective treatments for VSS; this includes both possible medications/pharmacological and additional noninvasive interventions

Methods include:

Brain imaging using the most powerful state-of-the-art neuroimaging techniques, including a 7-Tesla MRI

Positron emission tomography (PET) imaging to test the distribution of different chemical receptors in the brain

Receptor-Enriched Analysis of Functional Connectivity by Targets (REACT) approach

 Utilizing Mindfulness-Based Cognitive Therapy modified for VSS symptoms (MBCT-vision) to alter the brain’s visual network and neural pathways to alleviate symptoms

 Utilizing visual tests and blood samples

 Electroencephalography (EEG)


 Neuro-Optometric Rehabilitation Therapy (NORT) to strengthen visual function, alleviate symptoms, and improve quality of life

• Transcranial magnetic stimulation (TMS) / Repetitive transcranial magnetic stimulation (rTMS)

Principal investigators include:

 Dr. Francesca Puledda in association with Dr. Peter Goadsby, King’s College London

 Dr. Sui Wong, Guy’s and St Thomas’ NHS Foundation

 Dr. Christoph Schankin and Antonia Klein, Bern University Hospital

Dr. Victoria Pelak, University of Colorado (Funded by VSI in 2019 and delayed due to the pandemic, Dr. Pelak has stated that her study on rTMS for VSS study is still ongoing.)


Thank you again for your ongoing support!

For additional information, please access the following article: “4 VSI-Funded Research Studies On Visual Snow Syndrome“.

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